The M2ADL laboratory operates in the field of chemistry applied to cultural heritage. The research lines currently undertaken deal with the development of innovative analytical methodologies for the characterisation and localization of organic and inorganic compounds in objects of artistic and archaeological interest. Advanced non-invasive and micro-destructive spectroscopic techniques are used for this purpose, assisted by the chemometric analysis of the data. The aim of the proposed approaches is the study of alteration phenomena, the study of materials and execution techniques, the identifications of physico-chemical interactions originating the degradation processes and the evaluation of the effectiveness of new green materials for restoration.